Search on: U1 SMALL NUCLEAR RIBONUCLEOPROTEINS 
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Descriptor English:   Ribonucleoprotein, U1 Small Nuclear 
Descriptor Spanish:   Ribonucleoproteína Nuclear Pequeña U1 
Descriptor Portuguese:   Ribonucleoproteína Nuclear Pequena U1 
Synonyms English:   Small Nuclear Ribonucleoproteins, U1
U1 snRNP
U1 Small Nuclear Ribonucleoproteins  
Tree Number:   D12.776.157.725.500.875.600
D12.776.664.962.500.875.600
Definition English:   A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction. 
History Note English:   2000; U1 SNRNP was U1-RNP (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   30535 
Unique Identifier:   D017412 

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